Table 4.
Associations between micronutrients and mineral salts intake and RUNX3 methylation risk, according to CagA status
|
Total subjects |
CagA
(-) or H. pylori (-) |
CagA
(+) |
||||
| Methylated/ unmethylated | OR (95%CI)1 | Methylated/ unmethylated | OR (95%CI)1 | Methylated/ unmethylated | OR (95%CI)1 | |
| Protein | ||||||
| Low | 54/39 | 1.0 | 35/26 | 1.0 | 19/13 | 1.0 |
| High | 52/39 | 0.90 (0.50-1.64) | 37/27 | 0.95 (0.46-1.95) | 15/12 | 0.86 (0.29-2.57) |
| Fat | ||||||
| Low | 60/39 | 1.0 | 38/23 | 1.0 | 22/16 | 1.0 |
| High | 46/39 | 0.74 (0.21-1.35) | 34/30 | 0.66 (0.32-1.36) | 12/9 | 0.98 (0.30-3.25) |
| Carbohydrate | ||||||
| Low | 71/39 | 1.0 | 53/28 | 1.0 | 18/11 | 1.0 |
| High | 35/39 | 0.48 (0.25-0.91)3 | 19/25 | 0.41 (0.19-0.90)3 | 16/14 | 0.53 (0.15-1.91) |
| Vitamin A | ||||||
| Low | 57/39 | 1.0 | 36/27 | 1.0 | 21/12 | 1.0 |
| High | 49/39 | 0.73 (0.40-1.35) | 36/26 | 0.88 (0.42-1.86) | 13/13 | 0.51 (0.17-1.56) |
| Vitamin B1 | ||||||
| Low | 65/40 | 1.0 | 48/24 | 1.0 | 17/15 | 1.0 |
| High | 41/38 | 0.67 (0.36-1.22) | 24/29 | 0.42 (0.20-0.89)23 | 17/10 | 2.04 (0.63-6.62)2 |
| Vitamin B2 | ||||||
| Lo | 56/39 | 1.0 | 37/25 | 1.0 | 19/14 | 1.0 |
| High | 50/39 | 0.81 (0.44-1.48) | 35/28 | 0.77 (0.37-1.62) | 15/11 | 0.97 (0.33-2.85) |
| Vitamin C | ||||||
| Low | 66/39 | 1.0 | 50/31 | 1.0 | 16/8 | 1.0 |
| High | 40/39 | 0.56 (0.30-1.04) | 22/22 | 0.59 (0.27-1.29) | 18/17 | 0.38 (0.11-1.28) |
| Vitamin E | ||||||
| Low | 73/39 | 1.0 | 54/24 | 1.0 | 19/15 | 1.0 |
| High | 33/39 | 0.47 (0.26-0.88)3 | 18/29 | 0.29 (0.13-0.62)23 | 15/10 | 1.30 (0.42-4.05)2 |
1
Adjusted for age, sex, total energy intake;
2
Odds ratio (OR) was significantly different according to CagA status in a homogeneity test;
3
P value < 0.05 statistically significant difference.