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. 2013 Mar 20;13:248. doi: 10.1186/1471-2458-13-248

Table 1.

Respondents risk allocation in accordance with CRC screening guidelines

Risk category*  
At or slightly above average risk
• No personal history of bowel cancer.
 
• Either no close relatives with bowel cancer or one first-degree or second-degree relative with bowel cancer diagnosed at age 55 years or older.
Moderately increased risk
• One first-degree relative diagnosed before the age of 55 years (without potentially high-risk features listed below), or
 
• Two first-degree relatives or one first- and one second-degree relative(s) on the same side of the family (without potentially high-risk features listed below).
Potentially high risk
• Three or more first-degree or a combination of first-degree and second-degree relatives on the same side of the family diagnosed with bowel cancer (suspected HNPCC**), or
  • Two or more first-degree or second-degree relatives on the same side of the family diagnosed with bowel cancer, including the following risk feature: bowel cancer before the age of 50 years or at least one-relative with cancer of the endometrium, ovary, stomach, small bowel, renal pelvis, ureter, biliary tract or brain.

* Risk features potentially placing persons at possible increased risk including: personal history of adenoma, inflammatory bowel disease or suspected familial adenomatous polyposis (FAP) were not assessed in the survey. ** HNPCC (Hereditary non-polyposis colorectal cancer) also known as Lynch syndrome.