Table 2.
Cellular functions of proteins identified and gene ontology (GO) annotations from the saccharomyces genome database
| |
A |
B |
C |
|||
|---|---|---|---|---|---|---|
| |
Genome |
n = 6310 |
Peptides > 1 |
n = 438 |
Peptides = 1 |
n = 153 |
| GO term FUNCTION | Frequency | Percent | Frequency | Percent | Frequency | Percent |
| biological process unknown |
1217 |
19.3 |
33 |
7.5 |
14 |
9.2 |
| RNA metabolic process |
1210 |
19.2 |
64 |
14.6 |
20 |
13.1 |
| transport |
1047 |
16.6 |
88 |
20.1 |
33 |
21.6 |
| translation |
706 |
11.2 |
129 |
29.5 |
17 |
11.1 |
| transcription, DNA-dependent |
603 |
9.6 |
15 |
3.4 |
7 |
4.6 |
| response to stress |
594 |
9.4 |
61 |
13.9 |
16 |
10.5 |
| protein modification process |
583 |
9.2 |
22 |
5.0 |
11 |
7.2 |
| cell cycle |
527 |
8.4 |
18 |
4.1 |
6 |
3.9 |
| ribosome biogenesis |
411 |
6.5 |
50 |
11.4 |
11 |
7.2 |
| DNA metabolic process |
404 |
6.4 |
15 |
3.4 |
5 |
3.3 |
| chromosome organization |
398 |
6.3 |
18 |
4.1 |
6 |
3.9 |
| vesicle-mediated transport |
366 |
5.8 |
20 |
4.6 |
13 |
8.5 |
| response to chemical stimulus |
331 |
5.2 |
30 |
6.8 |
11 |
7.2 |
| mitochondrion organization |
318 |
5.0 |
22 |
5.0 |
8 |
5.2 |
| cellular membrane organization |
286 |
4.5 |
24 |
5.5 |
10 |
6.5 |
| heterocycle metabolic process |
269 |
4.3 |
44 |
10.0 |
15 |
9.8 |
| cellular carbohydrate metabolic process |
265 |
4.2 |
53 |
12.1 |
12 |
7.8 |
| cellular amino acid metabolic process |
239 |
3.8 |
63 |
14.4 |
17 |
11.1 |
| signaling |
235 |
3.7 |
8 |
1.8 |
6 |
3.9 |
| cytoskeleton organization |
228 |
3.6 |
16 |
3.7 |
11 |
7.2 |
| cellular lipid metabolic process |
223 |
3.5 |
10 |
2.3 |
4 |
2.6 |
| protein complex biogenesis |
212 |
3.4 |
17 |
3.9 |
10 |
6.5 |
| cellular protein catabolic process |
198 |
3.1 |
15 |
3.4 |
5 |
3.3 |
| cofactor metabolic process |
163 |
2.6 |
33 |
7.5 |
4 |
2.6 |
| generation of precursor metabolites and energy |
160 |
2.5 |
53 |
12.1 |
4 |
2.6 |
| meiosis |
157 |
2.5 |
7 |
1.6 |
2 |
1.3 |
| cellular homeostasis |
150 |
2.4 |
20 |
4.6 |
7 |
4.6 |
| chromosome segregation |
142 |
2.3 |
3 |
0.7 |
1 |
0.7 |
| fungal-type cell wall organization |
133 |
2.1 |
5 |
1.1 |
3 |
2.0 |
| vacuole organization |
130 |
2.1 |
12 |
2.7 |
3 |
2.0 |
| sporulation resulting in formation of a cellular spore |
128 |
2.0 |
10 |
2.3 |
3 |
2.0 |
| conjugation |
117 |
1.9 |
5 |
1.1 |
2 |
1.3 |
| cytokinesis |
110 |
1.7 |
4 |
0.9 |
3 |
2.0 |
| transposition |
108 |
1.7 |
1 |
0.2 |
0 |
0.0 |
| cellular component morphogenesis |
96 |
1.5 |
3 |
0.7 |
3 |
2.0 |
| protein folding |
88 |
1.4 |
27 |
6.2 |
3 |
2.0 |
| cellular respiration |
88 |
1.4 |
21 |
4.8 |
2 |
1.3 |
| cell budding |
85 |
1.3 |
6 |
1.4 |
3 |
2.0 |
| cellular aromatic compound metabolic process |
77 |
1.2 |
13 |
3.0 |
7 |
4.6 |
| vesicle organization |
77 |
1.2 |
2 |
0.5 |
3 |
2.0 |
| peroxisome organization |
67 |
1.1 |
2 |
0.5 |
0 |
0.0 |
| pseudohyphal growth |
66 |
1.0 |
5 |
1.1 |
0 |
0.0 |
| vitamin metabolic process |
63 |
1.0 |
2 |
0.5 |
1 |
0.7 |
| nucleus organization | 60 | 1.0 | 4 | 0.9 | 2 | 1.3 |
Peptides used for identification include only those having at least 95% confidence. (A) The distribution of 6310 proteins, (B) 438 proteins identified with more than one peptide and (C) 153 proteins identified with one peptide.