Table 1.

Frequency of MNGs at GD 19 in testes of p53-null and p53-heterozygous pups of dams dosed daily in utero with either corn oil (control) or 500 mg/kg/day DBP (treated) from GD 12 until birth. The MNG counts for each pup within a litter were averaged, and the dams were used as the unit of effect within a group for statistical analysis across groups. Dams were compared by a one-way ANOVA (minimum number of dams per group, n=3).

Frequency of MNGs at GD 19
	MNGs/mm2
p53-null DBP-treated	29.6 ± 8.9 *
p53-heterozygous DBP-treated	12.5 ± 3.2 †
p53-null control	8.2 ± 2.4 †
p53-heterozygous control	0.2 ± 0.2

Mean concentration ± SEM;

^*indicates p<0.05 compared to all groups,

^†indicates p<0.05 compared to p53-heterozygous control.