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. 2012 Aug 3;70(4):661–687. doi: 10.1007/s00018-012-1073-7

Fig. 5.

Fig. 5

Aurora A activities in cancer. Aurora A expression is elevated based on changes in DNA copy number, transcription, and/or changes in protein stability. Overexpressed Aurora A induces multiple categories of growth defect that promote cancer, outlined here schematically; see text for details