. 2013 Mar;23(2):110–116. doi: 10.1089/cap.2011.0136

Table 1.

Sample Characteristics for Clozapine-Treated Children Hospitalized at the National Institutes of Health Clinical Center (N=87)

	Mild neutropenia only compared with no HAEs					Moderate neutropenia compared with no HAEs					Mild neutropenia only compared with moderate neutropenia
	Lowest ANC≥2000 (n=43)	Lowest 1500≤ANC<2000 (n=27)	df	Test statistic	p	Lowest ANC≥2000 (n=43)	Lowest ANC<1500 (n=17)	df	Test statistic	p	Lowest 1500≤ANC<2000 (n=27)	Lowest ANC<1500 (n=17)	df	Test statistic	p
Gender
Male	17	19	1	6.313	0.012^a	17	14	1		0.003^a	19	14	1	0.799	0.371^a
Female	26	8				26	3		8.945		8	3
Ethnicity
African American	13	5	1	1.191		13	9	1			5	9	1	5.698
Not African American	30	22			0.275^a	30	8		2.705	0.100^a	22	8			0.017^a

	Mean	SD	Mean	SD				Mean	SD	Mean	SD				Mean	SD	Mean	SD
Age at NIH hospitalization (yr)	14.17	2.00	12.17	2.48	68	3.711	<.001^b	14.17	2.00	13.14	2.82	58	1.585	0.118^b	12.17	2.48	13.14	2.82	42	1.206	0.235^b
Dose at discharge (mg/day)	342	152	350	135	66	0.241	0.811^b	342	152	364	89	55	0.548	0.586^b	350	135	364	89	41	0.357	0.723^b
Length of stay (days)	114.1	44.7	114.7	46.7	63	0.049	0.961^b	114.1	44.7	126	30.6	55	1.018	0.313^b	114.7	46.6	126.8	30.6	36	0.890	0.380^b

^{^a}

χ² test.

^{^b}

Independent-samples t-test.

HAE, hematologic adverse effect; ANC, absolute neutrophil count.