Table 3.
Leukocyte count changes during malaria treatment
| On admission | Upon clearance of parasitaemia | n | P value | |
|---|---|---|---|---|
|
Severe P. falciparum |
|
|
|
|
| CRP, mg/L |
184 (108–373) |
49 (1–206) |
29 |
<0.0001 |
| Total leukocyte count, x 109/L |
6.8 (2.5-18.5) |
7.8 (3.1-16.4) |
40 |
0.0045 |
| Neutrophil count, x 109/L |
3.5 (1.2-10.4) |
4.0 (1.4-10.7) |
40 |
NS |
| Lymphocyte count, x 109/L |
0.9 (0.2-4.2) |
2.1 (0.2-5.8) |
40 |
<0.0001 |
| NLCR |
4.0 (0.9-17.0) |
2.1 (0.5-20.3) |
40 |
0.0011 |
|
Non-severe P. falciparum |
|
|
|
|
| CRP, mg/L |
96 (5–284) |
14 (1–250) |
116 |
<0.0001 |
| Total leukocyte count, x 109/L |
4.8 (1.3-13.4) |
5.6 (2.2-16.9) |
161 |
<0.0001 |
| Neutrophil count, x 109/L |
3.0 (0.6-8.8) |
2.5 (0.3-11.9) |
114 |
0.0075 |
| Lymphocyte count, x 109/L |
0.9 (0.2-3.1) |
2.0 (0.3-4.5) |
114 |
<0.0001 |
| NLCR | 3.3 (0.5-19.0) | 1.3 (0.3-11.0) | 114 | <0.0001 |