Table 6.
Common DE genes in SZ and BD patients as compared to control samples derived from the fourth study. Top twenty genes (BD) are shown.
| Gene symbol | FC (log2) SZ versus control |
FC (log2) BD versus control |
Gene title |
|---|---|---|---|
| DERL1 | −0.9218 | −0.59278 | Der1-like domain family, member 1 |
| DDX27 | −0.58735 | −0.55081 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 |
| NELL1 | −0.48395 | −0.49181 | NEL-like 1 (chicken) |
| WDR41 | −0.561422 | −0.47103 | WD repeat domain 41 |
| SST | −0.56168 | −0.47692 | Somatostatin |
| ZYX | −0.55832 | −0.4319 | Zyxin |
| SSR1 | −0.79829 | −0.41544 | Signal sequence receptor, alpha fibronectin |
| FSD1 | −0.4133 | −0.39578 | Type III and SPRY domain containing 1 |
| TRIM27 | −0.51857 | −0.39195 | Tripartite motif-containing |
| TESC | −0.546183 | −0.364501 | 27 Tescalcin |
| HES1 | 0.383441 | 0.32929 | Hairy and enhancer of split 1 |
| MT1H | 0.477326 | 0.329479 | (Drosophila) metallothionein 1H |
| GJA1 | 0.694821 | 0.332313 | Gap junction protein, alpha 1, 43 kDa |
| TRIL | 0.405464 | 0.343382 | TLR4 interactor with leucine-rich repeats |
| MT1X | 0.60052 | 0.35402 | Metallothionein 1X |
| AGXT2L1 | 0.816962 | 0.375859 | Alanine-glyoxylate aminotransferase 2-like 1 |
| GREB1 | 0.623598 | 0.418634 | Growth regulation by estrogen in breast cancer 1 |
| EMX2 | 0.975302 | 0.545582 | Empty spiracles homeobox |
| GPC5 | 0.772653 | 0.591493 | 2 glypican 5 |
| ALDH1L1 | 1.0583 | 0.599394 | Aldehyde dehydrogenase 1 family, member L1 |
Downregulation of genes in each disease state is represented with negative FC values (fold decrease) and upregulation with positive FC values. Most statistically significant genes, common in SZ and BD, are differentiated in similar way.