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Participant ratings (mean ± SEM) of methadone “Desire,” “Liking,” and “High” as a function of study drug (aprepitant or placebo) and time throughout the session (Day 2 and 9). Following 24 hrs of methadone abstinence, aprepitant or placebo was administered at time 0 and methadone was administered 60 minutes later. * Indicates a significant difference of less than 0.10.
