Figure 3.
Semiquantitative morphometric analysis of glomerular damage index. Figure summarizes the glomerular damage index (GDI) of animals in all the four groups. GDI was calculated on PAS stained sections at a magnification of ×400 with a scoring system of 0 to 4. 0 represents no lesion; 1+ represents sclerosis of <25% of the glomerulus; 2+ represents sclerosis of 25-50% of the glomerulus; 3+ represents 50-75% of the glomerulus and 4+ represents sclerosis of >75% of the glomerulus. Values represent the mean ± standard deviation (n= 4) of the samples. Significant difference between Con and Dia groups: #p< 0.05; ##p< 0.01; ###p< 0.001. Significant difference between Dia and Dia+AMG, Dia and Dia+AGE groups: *p< 0.05; ** p< 0.01; ***p< 0.001