Table 1.

Previously reported cases of salivary gland large cell neuroendocrine carcinoma

Reference	Age	Sex	Past history	Presenting complaints	Size of tumor	Location	FNAC findings	Immunohisto-chemical findings	Treatment	Outcome
Hui et al.[7]	n.r.	n.r.	n.r.	n.r.	n.r.	n.r.	not performed	n.r.	n.r.	n.r.
Larsson and Donner [8]	88	F	n.r.	mobile mass of neck	2cm	right parotid	undifferentiated carcinoma	Chr (−), Syn (+)	Op and Rx	3 years disease free
Nagao et al.[9]	72	F	n.r.	enlargement of neck	7cm	right parotid	large cell undifferentiated carcinoma	Chr (−), Syn (+)	Cx and Op and Rx	died 5 months after operation
Nagao et al.[9].	73	M	n.r.	enlargement of neck	3.3cm	right parotid	not performed	Chr (+), Syn (−)	Op and Rx	died 4 years after operation
Casas et al.[10]	74	M	n.r.	enlargement of neck	9cm	left parotid	large cell undifferentiated carcinoma	Chr (+), Syn (+)	Op and Rx	8 months disease free
Ueo et al.[11]	72	M	gastric cancer	enlargement of neck	4.5cm	right parotid	not performed	Chr (+), Syn (+)	Op and Rx	died 8 months after operation
Sowerby et al.[12]	81	M	none	facial paralysis	6cm	left submandibular	atypical lymphoid proliferation	Chr (−), Syn (+)	Cx and Rx	27 months disease free
This report	68	M	DM, colon cancer	abdominal pain enlargement of neck	5cm	right submandibular	poorly differentiated carcinoma	Chr (−), Syn (+)	none	died 1 month after symptom appeared

Chr = chromogranin; Cx = chemotherapy; DM = diabetes mellitus; FNAC = fine-needle aspiration cytology; n.r. = not recorded; Op = operation; Rx = radiation; Syn = synaptophysin.