Fig. 10.

Projections of the interaction energy correlation matrix on residue space are shown for ligand-loaded subunit b of the half-loaded state of Gal-7 (A), for residue R53 of subunit b of the half-loaded state (B) and for residue E87 of ligand-free subunit a within the same subunit (C) and with the opposing subunit b (D). Even with the various restrictions outlined in Materials and Methods, several thousand pairwise correlations, with correlation coefficients >0.5, were found for both ligand-free and ligand-loaded lectin.