Table 2.
Traditional cardiovascular risk factors, selected inflammatory markers, and ultrasonographic evaluation of cardiovascular system in the juvenile idiopathic arthritis (JIA) patients and the control group.
| JIA patients (n = 58) |
Control group (n = 36) |
P value* | |
|---|---|---|---|
| Traditional risk factors | |||
|
| |||
| Age, years | 13.0 (11.0–15.0) | 13.4 (12–15) | 0.37 |
| BMI, kg/m2 | 20.6 (16.8–22.2) | 19.4 (17.3–20.6) | 0.15 |
| BMI-SDS | 0.3 (0.0–0.8) | 0.1 (−0.5–0.5) | 0.03 |
| SBP, mm Hg | 117 (102–127) | 112 (103–117) | 0.02 |
| DBP, mm Hg | 67 (64–75) | 64 (57–69) | 0.03 |
| Total cholesterol, mmol/L | 4 (3.6–4.6) | 4 (3.5–4.4) | 0.60 |
| LDL-cholesterol, mmol/L | 2.1 (1.8–2.5) | 2 (1.8–2.4) | 0.63 |
| HDL-cholesterol, mmol/L | 1.4 (1.2–1.6) | 1.4 (1.2–1.7) | 0.40 |
| Triglycerides, mmol/L | 0.7 (0.6–1) | 0.7 (0.6–0.9) | 0.74 |
| Glucose, mmol/L | 4.8 (4.6–5.1) | 4.8 (4.6–5.0) | 0.75 |
| Insulin, mU/mL | 7.5 (4.1–11.5) | 6.6 (4.0–8.8) | 0.19 |
| HOMA index | 1.5 (0.9–2.4) | 1.4 (0.8–1.9) | 0.19 |
|
| |||
| Inflammatory markers | |||
|
| |||
| hsCRP, mg/L | 1.07 (0.16–3.84) | 0.04 (0.01–0.20) | <0.001 |
| Il-6, pg/ml | 2.3 (0.5–6.6) | 0.2 (0.2–0.8) | <0.001 |
| TNFα, pg/ml | 2.8 (1.0–32) | 0.7 (0.7–0.72) | <0.001 |
| Adiponectin, μg/mL | 11.3 (8.0–14.0) | 12.5 (8.0–16.0) | 0.510 |
|
| |||
| Ultrasonographic studies | |||
|
| |||
| Brachial artery, mm | 3.7 (3.3–4.4) | 3.6 (3.2–4.2) | 0.560 |
| FMD, % | 7.8 (5.1–9.1) | 11.1 (9.2–12.6) | <0.001 |
| IMT, mm | 0.50 (0.44–0.54) | 0.42 (0.39–0.45) | <0.001 |
| LVMi, g/m2.7 | 27.6 (24.5–29.5) | 22.9 (19.2–28.3) | =0.020 |
Values are presented as median (interquartile range), SBP: systolic blood pressure, DBP: diastolic blood pressure, HOMA index: index of insulin resistance, FMD: flow mediated dilatation of the right brachial artery, IMT: intima-media thickness of the common carotid arteries, and LVMi: indexed left ventricle mass.
*Mann-Whitney test.