Table 2.
Norepinephrine and Epinephrine Levels (pg/mL) before, during, and Immediately after Thermal Ablation of Pheochromocytoma Metastases*
| Baseline | Needle Placed in Lesion | Needle Manipulation | During RF Ablation | Current off after Maxed | During Subsequent RF Ablation | After RF Ablation (Needle out) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ablation Session |
NE | EPI | NE | EPI | NE | EPI | NE | EPI | NE | EPI | NE | EPI | NE | EPI | ||||
| 2 | 876 | 18 | 1,622 (185) | 10 (56) | 3,446 (393) | 26 (144) | 2,094 (239) | 100 (556) | — | 5,596 (639) | 33 (183) | — | ||||||
| 3 | 238 | 13 | 332 (139) | 62 (477) | — | 947 (398) | 91 (700) | — | — | — | ||||||||
| 4 | 237 | 66 | 420 (177) | 37 (56) | — | 294 (124) | 17 (26) | 653 (276) | 27 (41) | — | 585 (247) | 30 (45) | ||||||
| 4A | 539 | 14 | 1,172 (217) | 22 (157) | — | 2,743 (509) | 42 (300) | 2,199 (408) | 30 (214) | — | 676 (125) | 23 (164) | ||||||
| 4B | 297 | 2 | 479 (161) | 7 (350) | — | 1,047 (353) | 10 (500) | — | 995 (335) | 44 (2,200) | 945 (318) | 29 (1,450) | ||||||
| 5 | 170 | 21 | 140 (82) | 8 (38) | — | 135 (79) | 77 (367) | — | — | 86 (51) | 25 (119) | |||||||
| 6 | 14,845 | 25 | 16,273 (110) | 26 (104) | — | 16,896 (114) | 31 (124) | 11,130 (75) | 24 (96) | 20,706 (139) | 36 (144) | 14,111 (95) | 43 (172) | |||||
Note.—Values in parentheses are percentages of baseline measurements.
*
Normal plasma ranges: norepinephrine, 80–498 pg/mL; epinephrine, 4–83 pg/mL.