Table 2.
Echocardiographic Parameters
| Variable | Control (n=5) | BTHS (n=5) |
|---|---|---|
| HR (bpm) | 69 ± 14 (58-93) | 80 ± 18 (61-102) |
| SBP (mm/Hg) | 120 ± 8 (108-128) | 100 ± 13* (80-112) |
| DBP (mm/Hg) | 71 ± 13 (51-80) | 61 ± 14 (48-78) |
| LV structure | ||
| LVM (g) | 143 ± 12 (128-158) | 138 ± 33 (88-173) |
| EDV (mL) | 96 ± 11 (86-113) | 76 ± 18 (55-103) |
| ESV (mL) | 40 ± 7 (34-51) | 37 ± 16 (24-64) |
| LV systolic function | ||
| EF (%) | 58 ± 3 (55-61) | 52 ± 9 (38-61) |
| LVOT TVI (cm/s) | 19.5 ± 3.1 (16.8-23.9) | 15.7 ± 1.1 (14.1-16.9) |
| LV Sm (cm/s) | 11.2 ± 1.9 (10.0-14.5) | 9.0 ± 1.6 (7.0-11.5) |
| Global Strain (%) | -19.0 ± 2.5 (-16.3- -21.3) | -15.2 ± 2.4** (-12.4- -17.7) |
| LV diastolic function | ||
| E wave (cm/s) | 80 ± 14 (66-90) | 72 ± 7 (62-77) |
| E/A ratio | 1.7 ± 0.6 (1.1-2.4) | 1.8 ± 1.0 (1.2-3.6) |
| Em (cm/s) | 16.6 ± 2.8 (13.0-20.5) | 15.3 ± 0.7 (15.0-16.0) |
| E/Em | 4.4 ± 0.5 (3.9-4.5) | 3.7 ± 0.5 (3.1-4.3) |
BTHS: Barth syndrome, HR: heart rate, bpm: beats per minute, SBP: systolic blood pressure, DBP: diastolic blood pressure, mmHg: mL of mercury, LV: left ventricle, LVM: left ventricular mass measured by 2-D echocardiography, EDV: end diastolic volume, ESV: end systolic volume, EF: ejection fraction, LVET: left ventricular ejection time, Sm: systolic myocardial velocity averaged from septum and lateral wall, Em: myocardial velocity during early diastole averaged from septum and lateral wall.
*
p<0.01
**
p<0.05.