Fig. 2.

Effect of paclitaxel on LPS-induced renal tissue damage, BUN, and serum creatinine in mice. Male C57 mice were injected with 10 mg/kg LPS with or without 0.15 mg/kg paclitaxel. As a control, the sham group was injected with saline. Kidney tissues and blood samples were collected 16 h after treatment. (A) Kidney sections were stained with hematoxylin and eosin to review tubular damage. (B) Tubular damage scores of kidney cortex and OSOM. (C) BUN and serum creatinine. Data are shown as mean ± S.E.M. (n = 12). ^△P < 0.05 versus the sham group; ^#P < 0.05 versus the LPS group. Original magnification, ×200 in A.