Fig. 3.

Adenosine and CPA concentration-response curves (CRCs) for inhibition of neurogenic constrictions of sham and DOCA-salt MAs. (A) Adenosine and CPA inhibited neurogenic constriction in sham arteries. The CPA curve was significantly left-shifted, compared with the adenosine CRC (P < 0.05). (B and C) Adenosine- and CPA-induced inhibition of neurogenic constriction were reduced in DOCA-salt arteries, compared with sham arteries. Data are mean ± S.E.M. Data were analyzed using two-way analysis of variance (ANOVA) and Bonferoni’s post-hoc test. *Significantly different from sham arteries (P < 0.05).