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Inactivation of the human CYP2E1 7-EFC O-de-ethylation activity as a function of the PEITC:CYP2E1 concentration ratio. Assay conditions were as described in Materials and Methods. The percent of human CYP2E1 7-EFC O-deethylation activity remaining after complete inactivation was plotted against the molar ratio of PEITC to CYP2E1. The data shown represent the mean of three separate experiments.
