TABLE 1.
% Activity Remaining | % P450Remaining | % Heme Remaining | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
0 min | 10 min | After Dialysis | FrFresh Reductase | 0 min | 10 min | After Dialysis | 0 Min | 10 Min | After Dialysis | |
−PEITC, −NADPH | 100 | 91 ± 4 | 100 | 100 | 100 | 96 ± 8 | 100 | 100 | 100 ± 4 | 100 |
+PEITC,−NADPH | 82 ± 4 | 77 ± 2 | 82 ± 4 | 85 ± 9 | 103 ± 8 | 93 ± 10 | 104 ± 3 | 100 ± 1 | ||
+PEITC,+NADPH | 83 ± 5 | 19 ± 1 | 27 ± 4 | 26 ± 4 | 44 ± 3 | 42 ± 7 | 70 ± 2 | 64 ± 6 |
7-EFC, 7-ethoxy-4-(trifluoromethyl) coumarin; P450, cytochrome P450; PEITC, phenethyl isothiocyanate.