Skip to main content
. Author manuscript; available in PMC: 2013 Mar 26.
Published in final edited form as: Wiley Interdiscip Rev RNA. 2010 Nov-Dec;1(3):457–473. doi: 10.1002/wrna.26

FIGURE 2.

FIGURE 2

ARE/poly(U)-binding/degradation factor 1 proteins are generated by alternative pre-messenger ribonucleic acid (mRNA) splicing. The AUF1/HNRPD gene has 10 exons (not shown to scale). The start codon in exon 1 and the stop codon in exon 8 are highlighted. The domain structures are shown in increasing order of apparent molecular weights. The dimerization domain, RRM1, RRM2, and Q-rich domain common to all isoforms are highlighted. Alternatively spliced exons 2 and 7 are represented by the stripped box and the red box, respectively. (Reprinted with permission from Ref. 44 Copyright 1998 Elsevier).