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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: J Immunol. 2013 Mar 1;190(7):3732–3739. doi: 10.4049/jimmunol.1202964

Figure 2. Neutralizing activity of Fab19 or Fab19 inferred germline-reversion variants.

Figure 2

Activity was determined by plaque reduction (antibody concentration needed to reduce the number of RSV plaques by 60%). Greater values indicate less potent neutralizing activity. The range of antibody concentration tested was from 0.1 μg/mL to 200 μg/mL. Dotted line indicates upper limit of detection. Each bar represents the mean (± standard deviation) neutralization activity calculated from plaque reduction assays run in triplicate. * Indicates p < 0.05 compared to Fab19, as calculated by an unpaired t test.