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. 2013 Mar 26;8(3):e59693. doi: 10.1371/journal.pone.0059693

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© 2013 Chung et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Representative photomicrographs of trichrome staining. The CsA group showed typical striped interstitial fibrosis, and extracellular matrix deposition in the cortex (Original magnification x200). (B) Quantitative analysis of tubulointerstitial fibrosis. CsA administration increased tubulointerstitial fibrosis compared to VH and it was not reduced by treatment with hATMSCs. hATMSCs; human adipose tissue derived mesenchymal stem cells.