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. 2013 Mar 26;8(3):e59693. doi: 10.1371/journal.pone.0059693

Figure 6. Effect of hATMSCs infusion on apoptosis in rats with chronic CsA nephropathy.

Figure 6

(A) Representative photomicrographs of TUNEL staining in experimental groups (Original magnification x200). (B) Quantitative analysis of TUNEL-positive cells. CsA administration increased TUNEL-positive cell number compared to VH and treatment with hATMSCs further increased it (C) Western blot analysis of caspase-3 protein expression. Caspase-3 was activated after treatment with CsA and treatment with hATMSCs did not reduce it. hATMSCs; human adipose tissue derived mesenchymal stem cells.