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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Immunol. 2013 Feb 27;190(7):3798–3805. doi: 10.4049/jimmunol.1203194

Figure 2. Competition with the co-culture induced ligand in the in vitro invasion assay by large polymeric SR-A ligands.

Figure 2

A. Macrophages and ID8 tumour cells were co-cultured in the presence of fucoidan, poly I, poly G or poly C. Addition of known SR-A ligands can inhibit tumour cell invasion (p<0.01, t-test). Poly C served as a negative control. Data are represented as mean ± SEM of n=6. Representative data are shown from at least 3 independent experiments. B. Addition of 100μg/ml of poly I up to 6hr after the start of the macrophage: ID8 co-culture inhibits tumour cell invasion. When added after 9h there is no impact on the invasion assay.

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