Table 3. Clinical factors for candida esophagitis on uni- and multivariable analysis (n = 733).

Clinical factors	CE (+) (n = 62)	CE (−) (n = 671)	Odds ratio (95% CI)	P
Univariate analysis
Age (years)
<40	21	236	1 (referent)
≥40	41	435	1.06 (0.60–1.93)	0.84
Sex
Female	7	46	1 (referent)
Male	55	625	0.58 (0.24–1.59)	0.19
Sexual behavior
Heterosexual	23	249	1 (referent)
MSM	39	422	1.00 (0.57–1.80)	1.00
CD4+ cell count (cells/μL)
>200	19	388	1 (referent)
100-199	4	134	0.61 (0.20–1.82)
<100	39	149	5.35 (2.99–9.55)	<0.01
HIV-RNA VL (copies/mL)
≤40 (normal range)	10	376	1 (referent)
40<VL≤10,000	13	123	3.97 (1.70–9.29)
10,000<VL≤100,000	15	84	6.71 (2.91–15.5)
100,000< VL	24	88	10.3 (4.73–22.2)	<0.01
History of HAART
Without	30	158	1 (referent)
With	32	513	0.33 (0.19–0.58)	<0.01
GI symptoms
Without	35	435	1 (referent)
With	27	236	1.42 (0.81–2.48)	0.18
Multivariate analysis
CD4+ cell count (cells/μL)
>200	19	388	1 (referent)
100-199	4	134	0.43 (0.14–1.30)
<100	39	149	2.82 (1.46–5.46)	<0.01
HIV-RNA VL (copies/mL)
≤40 (normal range)	10	376	1 (referent)
40<VL≤10,000	13	123	3.67 (1.54–8.74)
10,000<VL≤100,000	15	84	5.34 (2.24–12.7)
100,000< VL	24	88	5.67 (2.39–13.4)	<0.01

Abbreviations: CE, Candida esophagitis; MSM, men who have sex with men; VL: viral load; HAART, highly active antiretroviral therapy.