Table 18. List of genes that exhibited increasing ranking across time points as revealed by the MNI analysis, with a peak at 12 week in the muscle of mice.

Gene accession No.	Gene symbol	Description	Fold change (HFD/ND)
			2wk	4wk	8wk	12wk
Muscle
Insulin resistance
NM_145435	Pyy	Peptide YY	1.4	1.4	1.3	1.5
Inflammation
NM_138648	Olr1	Oxidized low density lipoprotein (lectin-like) receptor 1	0.5	0.6	0.5	0.3
NM_009132	Scin	Scinderin	0.6	0.6	0.7	0.7
Cancer
NM_145833	Lin28	Lin-28 homolog (C. elegans)	0.7	0.7	0.7	0.7
NM_010358	Gstm1	Glutathione S-transferase, mu 1	1.3	1.4	1.4	1.3
NM_001029979	Safb2	Scaffold attachment factor B2	0.7	0.7	0.7	0.6
Olfactory transduction
NM_146750	Olfr689	Olfactory receptor 689	0.6	0.7	0.7	0.5
NM_146943	Olfr347	Olfactory receptor 347	1.2	1.3	1.2	1.5
Others
NM_009372	Tgif1	TG interacting factor 1	1.2	1.1	0.8	0.6
XM_887155	Igsf10	Immunoglobulin superfamily, member 10	0.7	0.5	0.6	0.4
NM_009418	Tpp2	Tripeptidyl peptidase II	1.2	1.4	1.2	1.5
NM_008118	Gif	Gastric intrinsic factor	0.8	0.7	0.7	0.8
NM_026972	Cd209b	CD209b antigen	0.9	0.8	0.6	0.7
NM_145358	Camkk2	Calcium/calmodulin-dependent protein kinase kinase 2, beta	1.2	1.2	1.3	1.2
BC051526	Cd22	CD226 antigen	0.8	0.9	0.9	0.7
NM_029946	4931407K02Rik	RIKEN cDNA 4931407K02 gene	1.3	1.1	1.2	1.3
NM_172652	4632411B12Rik	RIKEN cDNA 4632411B12 gene	1.7	1.4	1.4	1.9
NM_011598	Fabp9	Fatty acid binding protein 9, testis	0.8	0.8	0.9	0.7
NM_011023	Otx1	Orthodenticle homolog 1 (Drosophila)	0.7	0.7	0.7	0.5
NM_019579	Mpp5	Membrane protein, palmitoylated 5	0.5	0.5	0.6	0.3
NM_007555	Bmp5	Bone morphogenetic protein 5	0.9	0.9	0.8	0.8
NM_001039047	Trim58	Tripartite motif-containing 58	1.3	1.2	1.5	1.5
NM_020049	Slc6a14	Solute carrier family 6 (neurotransmitter transporter), member 14	0.8	0.6	0.7	0.6