Table 1. Characteristics of the study population.
| Variable | All patients | Estimation G. | Validation | Koeln | Essen |
| (n = 267) | (n = 170) | (n = 97) | (n = 183) | (n = 84) | |
| Age (years) | 43.8±12.1 | 43.9±11.9 | 43.7±12.6 | 44.8±12.6 | 41.8±10.8 |
| Female n, (%) | 141 (52.8) | 89 (52.4) | 52 (53.6) | 70 (38.3) | 71 (84.5) |
| BMI (kg/m2) | 37.0±12.7 | 37.2±13.0 | 36.6±12.9 | 29.0±6.1 | 52.4±7.6 |
| BMI normal/overweight/obese, n | 25/79/139 | 13/53/91 | 12/26/48 | 25/79/56 | 0/0/82 |
| Stage of fibrosis 0/1/2/3/4, n | 8/107/130/18/4 | 7/68/82/11/2 | 1/39/48/7/2 | 8/91/63/17/4 | 0/16/67/1/0 |
| Hypertension n, (%) | 112 (41.9) | 74 (43.5) | 38 (39.6) | 73 (39.9) | 39 (46.4) |
| Diabetes n, (%) | 53 (19.9) | 33 (19.4) | 20 (20.6) | 19 (10.4) | 34 (40.5) |
| Platelet (1.000/µl) | 265.0±80.0 | 265.4±80.9 | 264.3±78.7 | 247.8±71.5 | 299.0±85.2 |
| AST (IU/ml) | 36.8±32.4 | 34.9±22.8 | 40.2±44.7 | 40.9±37.5 | 27.9±13.5 |
| ALT (IU/ml) | 56.6±55.2 | 54.8±44.4 | 59.8±70.5 | 66.4±62.6 | 35.5±22.8 |
| AST/ALT ratio | 0.8±0.3 | 0.8±0.4 | 0.7±0.3 | 0.7±0.3 | 0.9±0.3 |
| <1,0 n, (%) | 214 (80.5) | 135 (79.4) | 79 (82.3) | 154 (84.2) | 60 (71.4) |
| ≥1,0 n, (%) | 52 (19.5) | 35 (20.6) | 17 (17.7) | 28 (15.4) | 24 (28.6) |
| GGT (IU/ml) | 111.4±186.1 | 128.8±222.7 | 80.5±82.8 | 136.8±201.2 | 56.2±133.4 |
| Total bilirubin (mg/dl) | 0.7±0.7 | 0.7±0.9 | 0.6±0.4 | 0.8±0.9 | 0.5±0.3 |
| Prothrombin time % | 101.5±14.6 | 100.3±15.8 | 103.8±11.9 | 103.7±13.5 | 97.0±15.8 |
| INR | 1.0±0.10 | 1.0±0.1 | 1.0±0.1 | 1.0±0.1 | 0.97±0.1 |
| Creatinine (mg/dl) | 0.9±0.7 | 0.9±0.8 | 0.8±0.2 | 0.9±0.8 | 0.8±0.5 |
| Albumin (g/l) | 44.6±3.4 | 44.8±3.5 | 44.4±3.3 | 44.6±3.4 | no data |
| Glucose (mg/dl) | 102.8±30.6 | 103.1±32.6 | 102.3±26.8 | 102.8±30.6 | 110.9±48.7 |
| Alkaline phosphatase (IU/ml) | 111.9±52.9 | 114.1±57.5 | 108.1±43.8 | 111.9±52.9 | no data |
| AFP (kU/l) | 3.0±1.8 | 3.1±2.0 | 2.7±1.4 | 3.0±1.8 | no data |
Data are shown as mean ± SD. Percentages (%) are given in brackets and refer to patients inside of respective subset. Abbreviations: BMI = body mass index; AST = aspartate aminotransferase; ALT = alanine aminotransferase; GGT = gamma glutamyl transferase; INR = International normalized ratio; AFP = alpha-fetoprotein.