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. Author manuscript; available in PMC: 2013 Mar 26.
Published in final edited form as: Crit Rev Biomed Eng. 2011;39(5):397–433. doi: 10.1615/critrevbiomedeng.v39.i5.40

FIGURE 8.

FIGURE 8

In vitro measurements by Ledo et al.167 of changes in nitric oxide (NO) and tissue O2 in rat hippocampus slice following pressure injection of different concentrations of N-methyl-D-aspartic acid (A) provides evidence for inhibition of O2 consumption by NO because tissue O2 increases with higher NO (B). Modified from Figs. 1 and 2 in Ledo et al.167,with permission from Free Radical Biology and Medicine.