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VDR inactivation leads to increased miR-155 expression. (A) RT-PCR analyses of baseline VDR, bic and TNFα transcripts in peritoneal macrophages harvested from WT and VDRKO mice; (B) Northern blot analysis of baseline miR-155 in peritoneal macrophages harvested from WT and VDRKO mice; (C and D) Time course of LPS-induction of bic transcript (C) and miR-155 (D) in WT and VDRKO BMDMs, quantitated by qPCR. *** P<0.001 vs. WT. n=3.
