Figure 5.
1,25-dihydroxyvitamin D down-regulates miR-155 and inflammatory cytokines in human peripheral blood mononuclear cells (PBMCs). Human PBMCs were pretreated with 1,25(OH)2D3 (20 nM) overnight followed by LPS stimulation of r4 hours. The transcript levels of TNFα (A), IL-6 (B), bic (C) and miR-155 (D) were then quantified by qPCR. *** P<0.001 vs. the rest.