Table V.
Multivariate associations of Burkitt lymphoma incidence with demographic, clinical, and treatment characteristics
| Characteristic | Incidence rate ratios* | 95% Confidence intervals |
|---|---|---|
| Base model | ||
| Gender | ||
| Female | 0.45 | 0.28, 0.71 |
| Male | Ref. | |
| Age at transplant | ||
| 0–19 | 3.49 | 2.08, 5.68 |
| 20–34 | 2.36 | 1.28, 4.10 |
| 35+ | Ref. | |
| Race/ethnicity | ||
| White, Non- Hispanic | Ref. | |
| All others ¶ | 0.93 | 0.59, 1.42 |
| Transplanted organ | ||
| Heart | 2.39 | 1.30, 4.31 |
| Kidney | Ref. | |
| Liver | 2.91 | 1.68, 5.09 |
| Other | 1.01 | 0.30, 2.59 |
| Baseline EBV serostatus | ||
| Negative | Ref. | |
| Positive | 0.34 | 0.13, 0.93 |
| Unknown/missing | 0.61 | 0.29, 1.44 |
| Time since transplant | ||
| <2 years | 0.12 | 0.04, 0.27 |
| 2–<3 years | 1.73 | 1.09, 2.70 |
| 3+ years | Ref. | |
| Additional variables, adjusted results | ||
| Polyclonal antibody | ||
| No | Ref. | |
| Yes | 0.64 | 0.27, 1.32 |
| IL2RA | ||
| No | Ref. | |
| Yes | 0.92 | 0.39, 1.87 |
| Azathioprine | ||
| No | Ref. | |
| Yes | 0.56 | 0.34, 0.89 |
| MMF | ||
| No | Ref. | |
| Yes | 1.08 | 0.67, 1.69 |
| Corticosteroids | ||
| No | Ref. | |
| Yes | 0.48 | 0.29, 0.82 |
*
The base model includes gender, age at transplant, race, transplanted organ, and EBV status. Estimates for each medication were adjusted for the variables in the base model, but not for each other.
¶
Other includes blacks, Hispanics, and Asians/Pacific Islanders.