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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Immunol. 2013 Feb 20;190(7):3109–3120. doi: 10.4049/jimmunol.1203422

Figure 3.

Figure 3

A hierarchy in the insulitis protection in Idd3+Idd5-sub-region(s) congenic strains. Non-diabetic females of the congenic Idd3 (Line 1098), Idd3+5.3 (Line 9246), Idd3+5.2+5.3 (Lines 9245 and 7380), and Idd3/5 (Line 6109) at 196 days of age were sacrificed and insulitis scored. Each diabetic mouse was assigned an insulitis score of ‘3’ indicated by an open symbol. For each group, the number (X) of pancreases that have an average insulitis score of zero was indicated on top of the x-axis and written as ‘+(X) zero’, because of the Log2 scale on the y-axis. Horizontal lines on the graph depict median values. Note that Idd3/5 strain had a median of zero. Each pair of strains is compared using Mann-Whitney U test. NS, not significant, p-value ≥0.05.