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. Author manuscript; available in PMC: 2014 Feb 26.
Published in final edited form as: Ann Neurol. 2013 Feb 26;73(2):170–179. doi: 10.1002/ana.23836

Table 4.

Multivariable-adjusted1 mean (95% CI) Digit Symbol Substitution Test (DSST), Stroop Test, and Rey Auditory Verbal Learning Test (RAVLT) scores at Year 25 by individual cardiovascular health components based upon the average of baseline, Year 7, and Year 25 levels, CARDIA (n = 2,932).

DSST (symbols) Stroop Test (points) RAVLT (words)
Body mass index
 Ideal health 69.7 (68.9, 70.5) 22.7 (22.0, 23.2) 8.1 (8.0, 8.3)
 Intermediate health 68.9 (68.0, 69.7) 22.7 (22.1, 23.3) 8.2 (8.0, 8.4)
 Poor hevalth 68.3 (67.3, 69.4) 24.3 (23.6, 25.1) 8.2 (7.9, 8.4)
  p-trend 0.04 0.002 >0.2
Diet score
 Ideal health 70.0 (66.1, 74.7) 23.1 (19.9, 26.3) 7.8 (6.9, 8.7)
 Intermediate health 69.9 (69.0, 70.8) 22.6 (21.9, 23.3) 8.3 (8.1, 8.5)
 Poor health 68.6 (67.9, 69.3) 23.3 (22.8, 23.8) 8.1 (8.0, 8.2)
  p-trend 0.03 0.1 >0.2
Smoking
 Ideal health 70.1 (69.5, 70.6) 22.6 (22.2, 23.1) 8.3 (8.2, 8.4)
 Intermediate health 67.3 (64.1, 70.4) 22.8 (20.4, 25.1) 7.9 (7.3, 8.6)
 Poor health 64.3 (62.9, 65.6) 25.3 (24.3, 26.3) 7.6 (7.3, 7.9)
  p-trend <0.001 <0.001 <0.001
Physical activity
 Ideal health 70.1 (69.4, 70.8) 22.6 (22.1, 23.1) 8.1 (8.0, 8.3)
 Intermediate health 68.2 (67.3, 69.0) 23.5 (22.9, 24.1) 8.4 (8.2, 8.5)
 Poor health 66.0 (64.1, 67.8) 24.3 (23.0, 25.8) 7.7 (7.3, 8.1)
  p-trend <0.001 0.006 >0.2
Total cholesterol
 Ideal health 69.2 (68.6, 69.8) 22.9 (22.4, 23.3) 8.3 (8.2, 8.4)
 Intermediate health 68.6 (67.8, 69.5) 23.5 (22.9, 24.2) 8.0 (7.8, 8.2)
 Poor health 70.5 (67.4, 73.6) 23.1 (20.8, 25.4) 7.5 (6.8, 8.1)
  p-trend >0.2 0.2 <0.001
Blood pressure
 Ideal health 69.9 (69.3, 70.6) 22.6 (22.1, 23.1) 8.3 (8.2, 8.4)
 Intermediate health 68.1 (67.3, 68.9) 23.5 (22.9, 24.1) 8.0 (7.8, 8.2)
 Poor health 63.4 (59.8, 67.1) 29.0 (26.3, 31.6) 8.0 (7.3, 8.7)
  p-trend <0.001 <0.001 0.008
Glucose
 Ideal health 69.3 (68.8, 69.9) 22.9 (22.4, 23.3) 8.2 (8.1, 8.3)
 Intermediate health 68.8 (67.4, 70.3) 23.9 (22.8, 25.0) 8.1 (7.8, 8.4)
 Poor health 62.2 (59.1, 65.4) 25.6 (23.3, 28.0) 7.5 (6.8, 8.1)
  p-trend 0.001 0.006 0.1
1

Adjusted for age (years), sex, race (black, white), educational attainment (years), alcohol use (average ml/d), and study center (Birmingham, Chicago, Minneapolis, Oakland).