Table 2.
Adjusted risk estimates of distant recurrence
| Multivariate analysis | |||||
|---|---|---|---|---|---|
| Parity groupa | Number of cases | Adjusted HRb,c | 95 % CI | p | 5-Year distant recurrence probability (%) |
| PABC <5 | N = 84 | 2.80 | 1.12–6.57 | 0.02 | 31.3 |
| Parous ≥5 | N = 168 | 1.01 | 0.48–2.15 | 0.97 | 19.9 |
| Nulliparous | N = 74 | 1.0 | – | – | 14.8 |
Hazard ratios and 95 % confidence intervals for all covariates included in the final model are described in Table 6 in the supplemental material. Clinical characteristics of the collapsed Parous ≥5 group can be viewed in Table 8 in the supplemental material
Parous ≥5, cases diagnosed five years or later from last childbirth
aPABC <5 cases had a mean followup time of 2.7 ± 2.7 years. Mean followup time for nulliparous was 3.2 ± 3.2 years and 3.5 ± 3.6 years for cases diagnosed ≥5
bAdjusted for tumor biologic subtype, clinical stage, year of diagnosis, and local recurrence
cHistologic subtype and grade were not univariately significant and were thus not included in the final multivariate models