Table 1.
Characteristics of the study groups, median (range) for (age, parasite density, IgG and IgG subclasses) regarding pregnancy duration
| Study groups variables | First trimester | Second trimester | Third trimester | P value |
|---|---|---|---|---|
|
Malaria-free control n=58 (48%) |
13 (22.4%) |
13 (22.4%) |
32 (55.2%) |
<0.001 |
|
Asymptomatic Malaria n=62 (52%) |
34 (54.8%) |
20 (32.3%) |
8 (12.9%) |
|
|
FcγRIIa genotypes | ||||
|
R/R131 n=41 (%) |
22 (53.7%) |
17 (41.5%) |
2 (4.9%) |
<0.001 |
|
R/H131 n=41 (%) |
20 (48.8%) |
11 (26.8%) |
10 (24.4%) |
|
|
H/H131 n=38 (%) |
5 (13.2%) |
5 (13.2%) |
28 (73.7%) |
|
|
FcγRIIa alleles | ||||
|
R 131 allele |
0.68 |
0.68 |
0.18 |
0.004 |
|
H 131 allele |
0.32 |
0.32 |
0.82 |
|
|
Median (range) for: | ||||
|
Age/years |
21 (18–26) |
22 (18–26) |
23 (18–26) |
0.046 |
|
Parasite density/μl |
1600 (250–2000) |
1400 (510–2000) |
1050 (250–2000) |
0.007 |
|
Specific antibody for AMA-1 | ||||
|
IgG |
1.28 (0.28- 6.04) |
1.28 (0.50- 7.30) |
2.76 (0.29- 6.90) |
0.003 |
|
IgG1 |
0.59 (0.11- 21–95) |
5.30 (0.16- 22.27) |
5.43 (0.05- 32.89) |
0.180 |
|
IgG2 |
0.04 (0.02- 5.64) |
2.11 (0.02- 5.73) |
2.16 (0.02- 6.10) |
0.040 |
|
IgG3 |
0.52 (0.01- 37.94) |
8.33 (0.12- 39.45) |
8.39 (0.09- 46.00) |
0.185 |
| IgG4 | 0.02 (0.01- 2.62) | 0.59 (0.01- 3.24) | 0.61 (0.01- 2.01) | 0.514 |