Table 3.
Likelihood values and parameter estimates for the FGF5 gene
| Models | ln La | Estimate of parameters | 2ΔLb(P-value) | Positively selected sites |
|---|---|---|---|---|
| M0:one-ratio |
−4450.77242 |
ω = 0.16615 |
|
|
|
Branch-specific models |
||||
|
Branch a (ancestral Cetacea) |
||||
| Two-ratio |
−4450.74677 |
ω0 = 0.16656, ω1 = 0.14336 |
0.0513 |
|
| (P = 0.8208) | ||||
|
Branch b (ancestral Odontoceti) |
||||
| Two-ratio |
−4447.80276 |
ω0 = 0.16253, ω1 = 1.04812 |
5.93932 |
|
|
(P= 0.0148) | ||||
|
Branch c (ancestral Mysticeti) |
||||
| Two-ratio |
−4449.912614 |
ω0 = 0.16491, ω1= 0.93251 |
1.719612 |
|
| (P = 0.189743) | ||||
|
Branch d (ancestral Cetartiodactyla) |
||||
| Two-ratio |
−4449.692636 |
ω0 = 0.16802, ω1 = 0.0001 |
2.159568 |
|
| (P = 0.1416845) | ||||
|
Branch e (ancestral Carnivora) |
||||
| Two-ratio |
−4450.028289 |
ω0 = 0.16284, ω1 = 0.28977 |
1.488262 |
|
| (P = 0.2224863) | ||||
|
Branch f (ancestral Chiroptera) |
||||
| Two-ratio |
−4450.762558 |
ω0 = 0.16637, ω1 = 0.14605 |
0.019724 |
|
| (P = 0.8883106) | ||||
|
Branch g (ancestral Rodentia) |
||||
| Two-ratio |
−4450.367662 |
ω0 = 0.16377, ω1 = 0.33139 |
0.809516 |
|
| (P = 0.3682634) | ||||
|
Branch h (ancestral Primates) |
||||
| Two-ratio |
−4450.765224 |
ω0 = 0.16585, ω1 = 0.17607 |
0.014396 |
|
| (P = 0.9044964) | ||||
|
Branch-site models |
||||
| Null |
−4370.04122 |
p0 = 0.80258, p1 = 0.19742, ω0 = 0.05816, ω1 = 1 |
|
|
|
Branch a (ancestral Cetacea) |
||||
| Alternative |
−4370.04122 |
p0 = 0.80258, p1 = 0.19742, p2a = 0, p2b = 0, ω0 = 0.05816, ω1 = 1, ω2 = 1 |
0 (P = 1) |
None |
|
Branch b (ancestral Odontoceti) |
||||
| Alternative |
−4365.28771 |
p0 = 0.46391, p1 = 0.12028, p2a = 0.33019, p2b = 0.08561, ω0 = 0.05123, ω1 = 1, ω2 = 2.03039 |
9.50702 |
K24E(0.945);P34Q(0.914);S68P(0.535);S74N(0.947);S84T(0.94) |
|
(P= 0.0086) | ||||
|
Branch c (ancestral Mysticeti) |
||||
| Alternative |
−4368.231030 |
p0 = 0, p1 = 0, p2a = 0.80784, p2b = 0.19216, ω0 = 0.05877, ω1 = 1, ω2 = 1 |
3.62038 |
M119T(0.777);V235A(0.937) |
| (P = 0.163623) | ||||
|
Branch d (ancestral Cetartiodactyla) |
||||
| Alternative |
−4370.041222 |
p0 = 0.80258, p1 = 0.19742, p2a = 0, p2b = 0, |
0 (P = 1) |
None |
| ω0 = 0.05816, ω1 = 1, ω2 = 1 | ||||
|
Branch e (ancestral Carnivora) |
||||
| Alternative |
−4370.041222 |
p0 = 0.80258, p1 = 0.19742, p2a = 0, p2b = 0, |
0 (P = 1) |
186T(0.571) |
| ω0 = 0.05816, ω1 = 1, ω2 = 1 | ||||
|
Branch f (ancestral Chiroptera) |
||||
| Alternative |
−4369.925398 |
p0 = 0.75669, p1 = 0.18750, p2a = 0.04473, p2b = 0.01108, ω0 = 0.05728, ω1 =1, ω2 =1 |
0.231644 |
84T(0.736) |
| (P = 0.8906337) | ||||
|
Branch g (ancestral Rodentia) |
||||
| Alternative |
−4370.041222 |
p0 = 0.80258, p1 = 0.19742, p2a =0, p2b =0, |
0 (P = 1) |
43G(0.621) |
| ω0 = 0.05816, ω1 = 1, ω2 = 1 | ||||
|
Branch h (ancestral Primates) |
||||
| Alternative |
−4370.041222 |
p0 = 0.80258, p1 = 0.19742, p2a = 0, p2b = 0, |
0 (P = 1) |
None |
| ω0 = 0.05817, ω1 = 1, ω2 = 1 |
Note: a, ln L is the log-likelihood score; b, likelihood ratio test (LRT) to detect positive selection.