Table 2.
Results of familial QTDT analyses including the whole population (n=200)
| |
Adjusted by the CD status |
Adjusted by the CD status, and NOD2 and NOD1 genotypes |
||
|---|---|---|---|---|
| p value | Z for mutated allele | p value | Z for mutated allele | |
| ASCA level |
0.024 |
−24.59 |
0.023 |
−24.58 |
| ASCA binary trait (positive/negative) |
0.05 |
−0.146 |
0.05 |
−0.145 |
| ALCA level |
0.0035 |
−17.08 |
0.0034 |
−17.17 |
| ALCA binary trait (positive/negative) | 0.0025 | −0.232 | 0.0026 | −0.230 |
The Z values reflect the strength of associations; negatives values reflect an association with a lower level of the trait under study. Positive values would reflect association with a higher level of the trait. NOD2, (R702W, G908R, 1007fs insC mutations) and the NOD1 +32656 genotypes were from Vasseur et al. [30].