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. Author manuscript; available in PMC: 2013 Apr 26.
Published in final edited form as: Cell. 2012 Oct 11;151(3):533–546. doi: 10.1016/j.cell.2012.09.027

Figure 1. Loqs-PB is Necessary and Sufficient to Maintain Female Germline Stem Cells.

Figure 1

(A) Drosophila and human Dicer partners.

(B) Drosophila germarium architecture. TF, terminal filament. CC, cap cells. SS, spectrosomes. Green, fusomes. Somatic cells are gray, germline are pink. Ovaries from 10-day-old females were stained with anti-Hu li tai shao (Hts) antibody (green) to detect the spectrosome and fusome, anti-Vasa antibody (red) to identify germ cells, and DAPI (blue) to highlight DNA. White arrowheads mark GSCs.

(C) The number of GSCs per germarium (mean ± SD) was measured for each genotype in 10–15 randomly selected germaria from pooled ovaries from >30 flies. Eight z axis images, spanning 20 μm, were acquired for each germarium. See also Figure S1 and Table S1.