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. Author manuscript; available in PMC: 2013 Apr 26.
Published in final edited form as: Cell. 2012 Oct 11;151(3):533–546. doi: 10.1016/j.cell.2012.09.027

Figure 3. Loqs-PB Changes the Size Distribution of Small RNAs Cleaved from Pre-miR-307a In Vivo.

Figure 3

The sequence, length, and abundance of ovary small RNAs from control and mutant females bearing Loqs-expressing transgenes was measured by deep sequencing.

(A) Mean length of all miRNA isomirs in the transgenic, mutant flies compared to control (w1118). Only miRNAs whose total isomir abundance was more than 100 ppm in w1118 were analyzed.

(B) Normalized abundance of each isomir of miR-307a* (blue) and miR-307a (red) for each genotype. Here and below, we considered only isomirs whose sequence variation reflected a change solely in the site Dicer cleaved.

(C) Abundance of miR-9b isomirs.

(D) Abundance of miR-316 isomirs.

See also Figure S5.