Table 1. The pair interaction energies (ΔE^Pair) of 6 mammalian PrP models under neutral pH condition.

The pair interaction energies were evaluated by summation of the calculated IFIEs between the residues on the element pairs. ^aThe average for the values of ΔE^Pair. ^bThe standard deviations σ for the values of the ΔE^Pair. ^*The varied ΔE^Pair among the 6 mammalian PrP^C; σ ≥ 20 kcal/mol. The blue-marked boxes are the maximum values (i.e., most repulsive interaction) among the PrP species. The red-marked boxes are the minimum values (i.e., most attractive interaction) among the PrP species.