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. 2012 Jan;2(1):16–20. doi: 10.1016/S2221-1691(11)60182-2

Table 2. Repository/Prophylactic activity of ethanolic leaves extract and fractions of M. scadens on P. berghei infection in mice (mean±SEM) (n=6).

Treatment Dose (mg/kg) Parasitaemia % Chemosuppression
Control (normal saline) 10 mL/kg 21.56±1.01
M. scadens crude extract 37 14.41±0.32* 33.16
74 12.88±0.40* 40.25
111 10.40±1.01* 51.76
Methanol fraction 74 12.15±1.04 43.64
Ethyl acetate fraction 74 13.54±1.04 37.19
Chloroform fraction 74 11.20±0.06* 48.05
Pyrimethamine 1.2 8.00±0.42* 62.89

*P<0.001 as compared with the control.