Table 2. Chemically intoxicated and its associated antioxidant activity of methanolic extract of D. carota seeds (DCSE) (Mean ± SEM).
Group (n=6) | SOD (u/mg protein) | CAT (u/mg protein) | GRD (u/mg protein) | GPX (u/mg protein) | GST (u/mg protein) | LPO (nmol MDA/mg liver protein) |
Control | 9.06 ± 0.06 | 55.93 ± 1.57 | 3.26 ± 0.08 | 11.26 ± 0.06 | 6.34 ± 0.13 | 7.70 ± 0.08 |
Toxic control (thioacetamide, 100 mg/kg, s.c) | 4.79 ± 0.09*** | 31.04 ± 0.87*** | 1.91 ± 0.02*** | 5.90 ± 0.11*** | 3.50 ± 0.23*** | 16.81 ± 0.30*** |
Standard (silymarin, 25mg/kg) | 8.65 ± 0.12*** | 55.36 ± 1.64*** | 3.28 ± 0.06*** | 9.85 ± 0.45*** | 5.69 ± 0.04*** | 10.86 ± 0.09*** |
DCSE (200mg/kg) | 5.15 ± 0.09*** | 35.39 ± 1.60*** | 2.25 ± 0.04*** | 6.99 ± 0.058*** | 3.48 ± 0.19*** | 8.29 ± 0.08*** |
DCSE (400mg/kg) | 7.18 ± 0.13*** | 42.79 ± 1.78*** | 2.70 ± 0.06*** | 9.20 ± 0.03*** | 5.07 ± 0.05*** | 7.26 ± 0.12*** |
***P < 0.001, a treated group animals compared with control.