Table 2. Effect of HRS on haematological parameters of rat in acetic acid induced IBD (n=6) (Mean ± SEM).
Parameters | Normal | Acetic acid control | Prednisolone (2 mg/kg) | HRS |
||
50 mg/kg | 100 mg/kg | 200 mg/kg | ||||
WBC ( X103 /µL) | 22.76 ± 0.76 | 9.76 ± 1.18 | 20.16 ± 1.05*** | 12.11 ± 0.72 | 14.15 ± 0.75*** | 18.60 ± 0.64*** |
RBC ( X106 /µL) | 13.38 ± 1.07 | 5.08 ± 0.55 | 12.13 ± 0.73*** | 7.51 ± 0.46 | 10.08 ± 0.70*** | 11.40 ± 0.27*** |
HGB (g /dL) | 15.96 ± 0.93 | 9.84 ± 0.69 | 14.03 ± 0.36*** | 10.13 ± 0.78 | 11.57 ± 0.75 | 13.08 ± 0.63* |
HCT (%) | 49.58 ± 1.59 | 34.61 ± 1.33 | 46.22 ± 0.90*** | 38.66 ± 1.83 | 40.12 ± 0.89 | 42.11 ± 1.45*** |
PLT ( X105 /µL) | 11.24 ± 0.55 | 5.19 ± 0.45 | 10.51 ± 0.41*** | 6.91 ± 0.42 | 8.21 ± 0.25* | 9.73 ± 0.33*** |
Data are analyzed by One Way ANOVA followed by Dunnett's test. *P < 0.05, **P < 0.01, ***P < 0.001 as compared to acetic acid control group.