Table 4. Effect of HRS on pathological changes of rat colon in acetic acid induced IBD.

Groups	Ulceration	Hyperemia	Necrosis	Edema	Cellular in filtration	Goblet cell hyperplasia
Normal	0	+	0	+	0	0
Acetic acid control	+++	+++	++++	+++	++++	++
Prednisolone (2 mg/kg)	+	++	+	++	++	+
HRS (200 mg/kg)	+	++	++	++	++	+

0: No abnormality detected; +: Damage/ active changes up to less than 25 %; ++: Damage/ active changes up to less than 50 %; +++: Damage/ active changes up to less 75 %; ++++: Damage/ active changes up to more than 75 %.