Table 1. Effect of methanolic leaf extract of C. gigantea extract on various biochemical parameters in paracetamol induced hepatotoxicity in rats (Mean ± SEM).

Design of treatment (n=6)	SGOT/AST (IU/L)	SGPT/ALT (IU/L)	ALP (IU/L)	TB (mg/dL)	TP(IU/L)
I. Control (1% Na.CMC, 1 mL/kg bw, p.o.)	70.50 ± 1.72	44.00 ± 1.29	164.00 ± 7.52	0.31 ± 0.02	9.16 ± 0.12
II. Paracetamol (1 g/kg bw)	134.00 ± 1.65	97.83 ± 0.90	438.00 ± 10.65	0.76 ± 0.01	6.50 ± 0.15
III. Silymarin (50 mg/kg bw)	98.16 ± 4.02***	78.97 ± 1.64***	216.00 ± 2.14***	0.52 ± 0.08***	8.78 ± 0.15***
IV. LCG (100 mg/kg bw)	116.50 ± 1.76***	84.00 ± 1.23**	304.83 ± 2.91***	0.64 ± 0.02**	7.58 ± 0.38***
V. LCG (200 mg/kg bw)	105.30 ± 1.83***	82.66 ± 1.33**	261.00 ± 2.39***	0.59 ± 0.01**	8.23 ± 0.22***

LCG- Methanolic leaf extract of C. gigantea. *P < 0.05, **P < 0.01, ***P < 0.001 as compared to Group II (paracetamol control).