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. 2012 Jun;2(6):461–464. doi: 10.1016/S2221-1691(12)60076-8

Table 2. Antidiabetic effect of ethanolic leaf extract and fractions of A. djalonensis on blood glucose level of alloxan-induced diabetic rats during acute study (mean±SEM) (n=6).

Treatments Dose (mg/kg) Blood glucose level (mg/dL) in hours
0 h 1 h 3 h 5 h 7 h
Control 10 mL 239.40±8.82 251.00±8.39 255.00±7.24 258.40±6.65 254.20±6.26
Extract 37 230.90±4.34 125.00±5.91 43.00±9.24 79.40±2.19b 85.20±2.05b
74 233.40±9.84 136.70±5.61c 37.50±13.86b 82.60±9.71c 86.00±8.54c
111 220.60±10.81 113.30±5.73a 36.00±8.08c 94.00±5.54c 95.40±16.00c
Chloroform fraction 74 240.60±19.50 197.60±2.72a 34.00±7.37c 133.30±2.51c 133.60±2.48c
Ethyl acetate fraction 74 239.80±19.62 227.30±12.74 38.30±8.73c 145.00±9.44b 150.30±9.73c
Methanol fraction 74 236.40±21.34 204.00±21.60a 38.66±16.25c 185.30±20.80c 184.80±20.70c
Glibenclamide 10 242.40±4.61 239.00±6.24 226.60±6.02c 207.80±9.25c 197.00±5.47c

a: P<0.05, b: P<0.01, c: P<0.001 when compared to control.