Table 1. Antidiabetic effect of KPFE in STZ-induced diabetic rats (Mean ± SEM).
Groups/Treatment | Blood glucose level (mg/dL) |
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Initial day | Day 7 | Day 14 | Day 21 | |
I: Vehicle | 115.27 ± 4.50 | 113.34 ± 3.80 | 112.70 ± 5.20 | 113.82 ± 2.40 |
II: STZ | 258.41 ± 2.30 | 294.47 ± 5.50 | 348.70 ± 5.30 | 402.00 ± 3.40 |
III: STZ + KPFE (250 mg/kg) | 288.45 ± 2.30 | 265.50 ± 4.30 | 194.27 ± 3.80* | 152.48 ± 2.70* |
IV: STZ + KPFE (500 mg/kg) | 298.29 ± 3.50 | 228.67 ± 4.20 | 189.75 ± 4.30* | 138.43 ± 3.50** |
V: STZ + Std. (10 mg/kg) | 274.27 ± 3.50 | 210.72 ± 4.22* | 125.41 ± 3.40** | 118.53 ± 3.50** |
*P<0.05, **P <0.001, When groups III, IV and V compared with diabetic control, i.e. group II.