Table 1. Effect of ethanolic leaf extract of M. scandens on body weight of alloxan - induced diabetic rats.
Treatment | Dose (mg/kg) | Day 0 | Day 15 | % increase/ decrease in body weight |
Control | 0.2 mL | 157.50±16.97 | 134.50±51.62 | -14.60 |
Extract | 37 | 170.60±18.06 | 159.60±5.82 | -6.45 |
74 | 174.48±25.76 | 167.80±2.41 | -3.83 | |
111 | 161.90±17.98 | 142.60±15.70 | -11.93 | |
Chloroform fraction | 74 | 143.80±25.98 | 140.10±2.60 | -2.57 |
Ethyl acetate fraction | 74 | 143.60±23.15 | 154.80±22.98 | +7.79 |
Methanol fraction | 74 | 165.20±14.73 | 167.70±24.0 | +1.51 |
Glibenclamide | 10 | 163.20±27.04 | 142.60±15.78 | -12.63 |
Data are represented as mean ± SEM. a P< 0.001, significant difference when compared with control group (n=6).