Table 1. Demographic and laboratorial measures of our non-diabetic NAFLD population regarding their serum ALT level.
Variables | Population with elevated ALT | Population with normal ALT | P value |
Gender [male (%)] | 172 (65.6) | 50 (60.2) | 0.430 |
BMI (kg/m2) | 29.7±3.9 | 29.7±4.9 | 0.960 |
BMI categorized | 0.647 | ||
Normal weight | 11 (4.9) | 5 (7.5) | - |
Overweight | 126 (55.8) | 36 (53.7) | - |
Obese class I | 62 (27.4) | 19 (28.4) | - |
Obese class II | 22 (9.7) | 4 (6.0) | - |
Obese class III | 5 (2.2) | 3 (4.5) | - |
Ultrasonography NAFLD grading | 0.003 | ||
Grade 1 | 125 (47.7) | 54 (65.1) | - |
Grade 2 | 90 (34.4) | 25 (30.1) | - |
Grade 3 | 47 (17.9) | 4 (4.8) | - |
Waist circumstance (cm) | 104±11 | 102±13 | 0.272 |
Waist>102 cm (male), >88 cm (female) | 155 (68.0) | 44 (59.5) | 0.205 |
Systolic blood pressure (mmHg) | 123±14 | 125±16 | 0.379 |
Diastolic blood pressure (mmHg) | 80±8 | 81±8 | 0.499 |
Total cholesterol (mg/dL) | 198±43 | 204±38 | 0.275 |
LDL-cholesterol (mg/dL) | 114.1±36.8 | 116.4±30.7 | 0.087 |
HDL-cholesterol (mg/dL) | 45.7±10.4 | 48.1±11.4 | 0.625 |
Triglyceride (mg/dL) | 206±136 | 218±120 | 0.486 |
Fasting insulin (mIU/L) | 12.8±5.8 | 10.4±5.5 | 0.002 |
Insulin resistance (HOMA>2.5) | 142 (62.3) | 34 (42.5) | 0.003 |
Uric acid (mg/dL) | 6.2±1.5 | 5.8±1.1 | 0.023 |
Alkaline phosphatase (IU/mL) | 193.2±67.9 | 178.8±68.1 | 0.093 |
Metabolic syndrome | 69 (28.2) | 22 (28.6) | 1.000 |
Central obesity | 155 (68) | 45 (60) | 0.209 |
High triglyceride (mg/dL) | 163 (62.7) | 55 (67.1) | 0.512 |
Low HDL (mg/dL) | 103 (41.2) | 31 (37.8) | 0.607 |
High blood pressure | 36 (14.3) | 15 (20.0) | 0.276 |
High fasting blood sugar | 34 (13) | 0 | <0.001 |