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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: J Am Coll Surg. 2012 Feb 17;214(4):478–488. doi: 10.1016/j.jamcollsurg.2011.12.015

Table 4. Cytokine Profiles For Trauma Patients With and Without Severe Head Injuries Stratified by In-Hospital Mortality.

Cytokine Severe head injury
(n=335)
No severe head injury
(n=687)
Survivor (n=687)
(n=290)
Mortality
(n=45)
p Value Survivor
(n=623)
Mortality
(n=64)
p Value
IL-1 2.7 [4.4] 2.7 [5.1] 0.98 2.7 [2.5] 2.7 [3.6] 0.55
IL-2 4.2 [11.4] 3.1 [13.2] 0.83 2.8 [10.2] 2.7 [4.7] 0.50
IL-4 30.3 [152.8] 108 [439.2] 0.001 31.2 [190.4] 112.7 [393.3] 0.001
IL-5 2.7 [2.8] 2.7 [6.9] 0.33 2.7 [1.6] 2.7 [1.7] 0.71
IL-6 116.1 [227.4] 162.5 [307.5] 0.07 162.0 [335.8] 247.4 [827.6] 0.003
IL-8 22.3 [45.5] 28.7 [56.8] 0.11 33.9 [53.2] 55.9 [126.9] 0.003
IL-10 48.0 [91.5] 50.8 [139.4] 0.69 53.1 [110.3] 66.9 [112.2] 0.21
IL-12 3.4 [10.1] 3.2 [12.6] 0.85 2.7 [5.4] 2.7 [5.2] 0.70
IFN 4.5 [11.5] 4.1 [15.1] 0.85 3.0 [7.5] 2.7 [5.9] 0.84
GMCSF 5.1 [8.8] 4.9 [9.2] 0.84 3.6 [6.3] 4.9 [11.2] 0.20
TNF-α 4.5 [6.0] 4.8 [9.0] 0.38 5.2 [7.2] 7.5 [10.1] 0.01